Dietary Choline Intake Is Directly Associated with Bone Mineral Density in the Hordaland Health Study [Nutrition and Disease]

Background: Choline is an important nutrient either obtained from a variety of foods or synthesized endogenously, and it is the precursor of betaine. We previously reported positive associations between plasma free choline and bone mineral density (BMD). Animal studies suggest an impact of dietary choline on bone metabolism, but the role of dietary intake of…