Low oxygen reverses mitochondrial disease in mice Hypoxia reverses brain damage caused by mitochondrial dysfunction, a team finds. The approach might one day point to new therapies for people with Leigh syndrome and other mitochondrial disorders. Low oxygen reverses mitochondrial disease in mice Source: Science Daily Healthy Aging
Stem cell transplants may advance ALS treatment by repair of blood-spinal cord barrier Researchers show that bone marrow stem cell transplants helped improve motor functions and nervous system conditions in mice with the disease Amyotrophic Lateral Sclerosis (ALS) by repairing damage to the blood-spinal cord barrier. The researchers say the results of their experiment are…
Prediction of conversion to Alzheimer’s disease with longitudinal measures and time-to-event data Predicting the timing of Alzheimer’s disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal change information of clinical and neuroimaging markers, in addition to baseline characteristics, according to projections made by investigators. In a new…
Stem cells may be the key to staying strong in old age A new study, performed in mice, could lead to new approaches to help people stay stronger in old age. The study challenges conventional wisdom with results suggesting that loss of muscle stem cells is the main driving force behind muscle decline in old…
Overall geriatric health during androgen deprivation therapy evaluated Androgen drives many prostate cancers. But the body uses androgen for muscle growth and maintenance, among other functions. An ongoing study evaluates the effects of androgen deprivation therapy not just on patients’ physical function but on global geriatric health, including skills of daily living. Because the study…
Mechanisms of Action of Probiotics and the Gastrointestinal Microbiota on Gut Motility and Constipation Constipation is a common and burdensome gastrointestinal disorder that may result from altered gastrointestinal motility. The effect of probiotics on constipation has been increasingly investigated in both animal and human studies, showing promising results. However, there is still uncertainty regarding the…
Gut microbes linked to brain structure in people with irritable bowel syndrome Research shows for the first time an association between the gut microbiota and the brain regions involved in the processing of sensory information from their bodies. Also, the researchers gained insight into the connections among childhood trauma, brain development and gut microbiome composition. …
Ignored? Better a ‘no’ than no answer at all After experiencing social exclusion, a minimum of attention suffices to reduce individuals’ negative emotions. Even rejection or unkind comments are better for well-being than being ignored by other people. This finding has important implications for the treatment of applicants during selection processes. Ignored? Better a ‘no’…
Group rituals can make us biased against outsiders From our greetings to our celebrations to how we take our coffee, everyday life is full of shared rituals. The effort and commitment involved in these rituals can help us bond with others — but new research suggests that they may also push us away from those…
One in five surgical weight-loss patients take prescription opioids seven years after surgery While the proportion of adults with severe obesity using prescription opioids initially declines in the months after bariatric surgery, it increases within a matter of years, eventually surpassing pre-surgery rates of patients using the potentially addictive pain medications, according to new research. …