Stem cell transplants may advance ALS treatment by repair of blood-spinal cord barrier

Stem cell transplants may advance ALS treatment by repair of blood-spinal cord barrier Researchers show that bone marrow stem cell transplants helped improve motor functions and nervous system conditions in mice with the disease Amyotrophic Lateral Sclerosis (ALS) by repairing damage to the blood-spinal cord barrier. The researchers say the results of their experiment are…

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Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

Prediction of conversion to Alzheimer’s disease with longitudinal measures and time-to-event data Predicting the timing of Alzheimer’s disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal change information of clinical and neuroimaging markers, in addition to baseline characteristics,  according to projections made by investigators. In a new…

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Overall geriatric health during androgen deprivation therapy evaluated

Overall geriatric health during androgen deprivation therapy evaluated Androgen drives many prostate cancers. But the body uses androgen for muscle growth and maintenance, among other functions. An ongoing study evaluates the effects of androgen deprivation therapy not just on patients’ physical function but on global geriatric health, including skills of daily living. Because the study…

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Mechanisms of Action of Probiotics and the Gastrointestinal Microbiota on Gut Motility and Constipation

Mechanisms of Action of Probiotics and the Gastrointestinal Microbiota on Gut Motility and Constipation Constipation is a common and burdensome gastrointestinal disorder that may result from altered gastrointestinal motility. The effect of probiotics on constipation has been increasingly investigated in both animal and human studies, showing promising results. However, there is still uncertainty regarding the…

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