Blood test identifies key Alzheimer’s marker Measures of amyloid beta in the blood have the potential to help identify people with altered levels of amyloid in their brains or cerebrospinal fluid, new research shows. Currently, the only way to detect amyloid beta in the brain is via PET scanning, which is expensive and not widely…
Steering an enzyme’s ‘scissors’ shows potential for stopping Alzheimer’s disease Scientists find that changing where an enzyme cuts amyloid beta precursor protein can determine whether Alzheimer’s disease develops. Steering an enzyme’s ‘scissors’ shows potential for stopping Alzheimer’s disease Source: Science Daily Healthy Aging
New discovery in motor neuron disease and dementia could pave the way to novel treatments A new discovery could help slow down the progression of neurodegenerative diseases such as motor neuron disease (MND), dementia and neurological decline associated with aging. New discovery in motor neuron disease and dementia could pave the way to novel treatments …
Low oxygen reverses mitochondrial disease in mice Hypoxia reverses brain damage caused by mitochondrial dysfunction, a team finds. The approach might one day point to new therapies for people with Leigh syndrome and other mitochondrial disorders. Low oxygen reverses mitochondrial disease in mice Source: Science Daily Healthy Aging
Prediction of conversion to Alzheimer’s disease with longitudinal measures and time-to-event data Predicting the timing of Alzheimer’s disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal change information of clinical and neuroimaging markers, in addition to baseline characteristics, according to projections made by investigators. In a new…
Overall geriatric health during androgen deprivation therapy evaluated Androgen drives many prostate cancers. But the body uses androgen for muscle growth and maintenance, among other functions. An ongoing study evaluates the effects of androgen deprivation therapy not just on patients’ physical function but on global geriatric health, including skills of daily living. Because the study…
Stem cells may be the key to staying strong in old age A new study, performed in mice, could lead to new approaches to help people stay stronger in old age. The study challenges conventional wisdom with results suggesting that loss of muscle stem cells is the main driving force behind muscle decline in old…
Fasting glucose as a marker for greater weight loss on a high-fiber, low-glycemic diet A Preliminary study finds that study participants with high fasting plasma glucose lost more weight than those with low fasting plasma glucose when following a high-fiber, low-glycemic load diet. Fasting glucose as a marker for greater weight loss on a high-fiber,…
Study identifies potential biomarker for Alzheimer’s disease In one of the largest studies to date to use metabolomics, the study of compounds that are created through various chemical reactions in the body, researchers have been able to identify new circulating compounds associated with the risk of developing dementia and Alzheimer’s disease (AD). The findings point…
Poor diet, plus Alzheimer’s gene, may fuel disease Mice carrying a genetic risk factor for the disease quickly developed brain plaques after 12 weeks on a poor diet, research indicates. Poor diet, plus Alzheimer’s gene, may fuel disease Source: Science Daily Healthy Aging