DNA vaccine protects against toxic proteins linked to Alzheimer's

DNA vaccine protects against toxic proteins linked to Alzheimer’s A new DNA vaccine, when delivered to the skin, prompts an immune response that produces antibodies to protect against toxic proteins associated with Alzheimer’s disease — without triggering severe brain swelling that earlier antibody treatments caused in some patients. DNA vaccine protects against toxic proteins linked…

Brain development and aging

Brain development and aging The brain is a complex organ — a network of nerve cells, or neurons, producing thought, memory, action, and feeling. How does this complex system change from childhood to adulthood to late life in order to maintain optimal behavioral responses? These questions were put to the test by psychologists who studied…

Improving control of age-related obesity

Improving control of age-related obesity The function and distribution of adipose tissue in the body change during the course of life. Beige fat cells, a special type of adipocytes, have the capability to use energy reserves – fatty deposits – by generating heat in a process known as thermogenesis. With increasing age, beige adipocytes take…

Telomere length predicts cancer risk

Telomere length predicts cancer risk The length of the ‘caps’ of DNA that protect the tips of chromosomes may predict cancer risk and be a potential target for future therapeutics. Longer-than-expected telomeres — which are composed of repeated sequences of DNA and are shortened every time a cell divides — are associated with an increased…

Link between common prostate cancer treatment, dementia detailed in new study

Link between common prostate cancer treatment, dementia detailed in new study A new analysis of patients who have undergone treatment for prostate cancer shows a connection between androgen deprivation therapy (ADT) — a testosterone-lowering therapy and a common treatment for the disease — and dementia, according to researchers. Link between common prostate cancer treatment, dementia…

Biological age-predicting 'epigenetic clock' for studying how to extend lifespan

Biological age-predicting ‘epigenetic clock’ for studying how to extend lifespan In order to measure and test the effects of interventions in the lab, investigators have developed an age-predicting clock designed for studies in mice. The new clock accurately predicts mouse biological age and the effects of genetic and dietary factors, giving the scientific community a…