Zinc Supplementation Does Not Alter Indicators of Insulin Secretion and Sensitivity in Black and White Female Adolescents [Nutrition and Disease]

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Zinc Supplementation Does Not Alter Indicators of Insulin Secretion and Sensitivity in Black and White Female Adolescents [Nutrition and Disease] Background: Zinc is a micronutrient involved in the production of, and peripheral sensitivity to, pancreatic β cell–derived insulin. To our knowledge, the effect of zinc supplementation on insulin outcomes, and potential risk of diabetes, in…

Intragastric Lysine Lowers the Circulating Glucose and Insulin Responses to a Mixed-Nutrient Drink without Slowing Gastric Emptying in Healthy Adults [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

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Intragastric Lysine Lowers the Circulating Glucose and Insulin Responses to a Mixed-Nutrient Drink without Slowing Gastric Emptying in Healthy Adults [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions] Background: Lysine is reported to lower the glycemic response to oral glucose in humans and, albeit at high loads, to slow gastric emptying of glucose and decrease food intake…

Iron, Zinc, Folate, and Vitamin B-12 Status Increased among Women and Children in Yaounde and Douala, Cameroon, 1 Year after Introducing Fortified Wheat Flour [Community and International Nutrition]

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Iron, Zinc, Folate, and Vitamin B-12 Status Increased among Women and Children in Yaounde and Douala, Cameroon, 1 Year after Introducing Fortified Wheat Flour [Community and International Nutrition] Background: Few data are available on the effectiveness of large-scale food fortification programs. Objective: We assessed the impact of mandatory wheat flour fortification on micronutrient status in…

Biotin: From Nutrition to Therapeutics [Recent Advances in Nutritional Sciences]

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Biotin: From Nutrition to Therapeutics [Recent Advances in Nutritional Sciences] Although frank symptomatic biotin deficiency is rare, some evidence suggests that marginal biotin deficiency occurs spontaneously in a substantial proportion of women during normal human pregnancy and might confer an increased risk of birth defects. Herein I review 1) advances in assessing biotin status, including…

Vitamin C induces specific demethylation of H3K9me2 in mouse embryonic stem cells via Kdm3a/b

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Vitamin C induces specific demethylation of H3K9me2 in mouse embryonic stem cells via Kdm3a/b Histone methylation patterns regulate gene expression and are highly dynamic during development. The erasure of histone methylation is carried out by histone demethylase enzymes. We had previously shown that v… Vitamin C induces specific demethylation of H3K9me2 in mouse embryonic stem…

Insufficient levels of Vitamin D in pregnancy detrimental to child development

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Insufficient levels of Vitamin D in pregnancy detrimental to child development Vitamin D deficiency in expectant mothers during pregnancy has a negative effect on the social development and motor skills of pre-school age children, a new study reports. Insufficient levels of Vitamin D in pregnancy detrimental to child development Source: Science Daily Nutrition Research

Should We Restrict Vitamin A Intake, a Minor Contributor to Plasma Retinol Turnover, When Using Retinol Isotope Dilution Equations to Estimate an Individuals Vitamin A Status, or Should Vitamin A Balance Be Maintained? [Issues and Opinions]

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Should We Restrict Vitamin A Intake, a Minor Contributor to Plasma Retinol Turnover, When Using Retinol Isotope Dilution Equations to Estimate an Individuals Vitamin A Status, or Should Vitamin A Balance Be Maintained? [Issues and Opinions] We discuss whether dietary vitamin A intake should be restricted or maintained at balance when retinol isotope dilution equations…

Low Calcium Intake in Midpregnancy Is Associated with Hypertension Development within 10 Years after Pregnancy: The Norwegian Mother and Child Cohort Study [Nutritional Epidemiology]

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Low Calcium Intake in Midpregnancy Is Associated with Hypertension Development within 10 Years after Pregnancy: The Norwegian Mother and Child Cohort Study [Nutritional Epidemiology] Background: Low dietary calcium intake may be a risk factor for hypertension, but studies conflict. Objective: We evaluated the ability to predict hypertension within 10 y after delivery based on calcium…