Pre-clinical study suggests Parkinson's could start in gut endocrine cells

Pre-clinical study suggests Parkinson’s could start in gut endocrine cells A potential new mechanism has been identified in both mice and human endocrine cells that populate the small intestines. Inside these cells is a protein called alpha-synuclein, which is known to go awry and lead to damaging clumps in the brains of Parkinson’s patients, as…

Genetic modifier for Huntington's disease progression identified

Genetic modifier for Huntington’s disease progression identified Researchers have developed a novel measure of disease progression for Huntington’s disease, which enabled them to identify a genetic modifier associated with how rapidly the disease progresses. Genetic modifier for Huntington’s disease progression identified Source: Science Daily Mind & Brain

Gene variant protecting against Alzheimer's disease decreases plasma beta-amyloid levels

Gene variant protecting against Alzheimer’s disease decreases plasma beta-amyloid levels The APP gene variant protecting against Alzheimer’s disease significantly decreases plasma beta-amyloid levels in a population cohort. This is a very significant discovery, as many on-going drug trials in the field of Alzheimer’s disease focus on decreasing beta-amyloid levels in the brain tissue. According to…

Predicting cognitive deficits in people with Parkinson's disease

Predicting cognitive deficits in people with Parkinson’s disease Parkinson’s disease is commonly thought of as a movement disorder, but after years of living with the disease, approximately 25 percent of patients also experience deficits in cognition that impair function. A newly developed research tool may help predict a patient’s risk for developing dementia and could…

Alzheimer's disease study links brain health, physical activity

Alzheimer’s disease study links brain health, physical activity People at risk for Alzheimer’s disease who do more moderate-intensity physical activity, but not light-intensity physical activity, are more likely to have healthy patterns of glucose metabolism in their brain, according to a new study. Alzheimer’s disease study links brain health, physical activity Source: Science Daily Healthy…