Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

Prediction of conversion to Alzheimer’s disease with longitudinal measures and time-to-event data Predicting the timing of Alzheimer’s disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal change information of clinical and neuroimaging markers, in addition to baseline characteristics,  according to projections made by investigators. In a new…

Stem cell transplants may advance ALS treatment by repair of blood-spinal cord barrier

Stem cell transplants may advance ALS treatment by repair of blood-spinal cord barrier Researchers show that bone marrow stem cell transplants helped improve motor functions and nervous system conditions in mice with the disease Amyotrophic Lateral Sclerosis (ALS) by repairing damage to the blood-spinal cord barrier. The researchers say the results of their experiment are…

Gut microbes linked to brain structure in people with irritable bowel syndrome

Gut microbes linked to brain structure in people with irritable bowel syndrome Research shows for the first time an association between the gut microbiota and the brain regions involved in the processing of sensory information from their bodies. Also, the researchers gained insight into the connections among childhood trauma, brain development and gut microbiome composition. …