Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

Prediction of conversion to Alzheimer’s disease with longitudinal measures and time-to-event data Predicting the timing of Alzheimer’s disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal change information of clinical and neuroimaging markers, in addition to baseline characteristics,  according to projections made by investigators. In a new…

Stem cell transplants may advance ALS treatment by repair of blood-spinal cord barrier

Stem cell transplants may advance ALS treatment by repair of blood-spinal cord barrier Researchers show that bone marrow stem cell transplants helped improve motor functions and nervous system conditions in mice with the disease Amyotrophic Lateral Sclerosis (ALS) by repairing damage to the blood-spinal cord barrier. The researchers say the results of their experiment are…

Gut microbes linked to brain structure in people with irritable bowel syndrome

Gut microbes linked to brain structure in people with irritable bowel syndrome Research shows for the first time an association between the gut microbiota and the brain regions involved in the processing of sensory information from their bodies. Also, the researchers gained insight into the connections among childhood trauma, brain development and gut microbiome composition. …

One in five surgical weight-loss patients take prescription opioids seven years after surgery

One in five surgical weight-loss patients take prescription opioids seven years after surgery While the proportion of adults with severe obesity using prescription opioids initially declines in the months after bariatric surgery, it increases within a matter of years, eventually surpassing pre-surgery rates of patients using the potentially addictive pain medications, according to new research. …

Trigger for autoimmune disease identified

Trigger for autoimmune disease identified Researchers have identified a trigger for autoimmune diseases such as lupus, Crohn’s disease and multiple sclerosis. The findings help explain why women suffer autoimmune disease more frequently than men, and suggest a therapeutic target to prevent autoimmune disease in humans. Trigger for autoimmune disease identified Source: Science Daily Mind &…

Trying new marijuana products and edibles is associated with unexpected highs

Trying new marijuana products and edibles is associated with unexpected highs Unexpected highs are a consequence of using new marijuana products and edibles, products that have flooded the marijuana market since legalization of recreational marijuana use. Trying new marijuana products and edibles is associated with unexpected highs Source: Science Daily Mind & Brain

Neuronal targets to restore movement in Parkinson's disease model

Neuronal targets to restore movement in Parkinson’s disease model Researchers have identified two groups of neurons that can be turned on and off to alleviate the movement-related symptoms of Parkinson’s disease. The activation of these cells in the basal ganglia relieves symptoms for much longer than current therapies, like deep brain stimulation and pharmaceuticals. The…