Improving control of age-related obesity

Improving control of age-related obesity The function and distribution of adipose tissue in the body change during the course of life. Beige fat cells, a special type of adipocytes, have the capability to use energy reserves – fatty deposits – by generating heat in a process known as thermogenesis. With increasing age, beige adipocytes take…

Whole-Grain Intake, Reflected by Dietary Records and Biomarkers, Is Inversely Associated with Circulating Insulin and Other Cardiometabolic Markers in 8- to 11-Year-Old Children [Nutrition and Disease]

Whole-Grain Intake, Reflected by Dietary Records and Biomarkers, Is Inversely Associated with Circulating Insulin and Other Cardiometabolic Markers in 8- to 11-Year-Old Children [Nutrition and Disease] Background: Whole-grain consumption seems to be cardioprotective in adults, but evidence in children is limited. Objective: We investigated whether intakes of total whole grain and dietary fiber as well…

Circulating Vitamin K Is Inversely Associated with Incident Cardiovascular Disease Risk among Those Treated for Hypertension in the Health, Aging, and Body Composition Study (Health ABC) [Nutritional Epidemiology]

Circulating Vitamin K Is Inversely Associated with Incident Cardiovascular Disease Risk among Those Treated for Hypertension in the Health, Aging, and Body Composition Study (Health ABC) [Nutritional Epidemiology] Background: A role for vitamin K in coronary artery calcification (CAC), a subclinical manifestation of cardiovascular disease (CVD), has been proposed because vitamin K–dependent proteins, including the…

Intestinal Barrier Function and the Gut Microbiome Are Differentially Affected in Mice Fed a Western-Style Diet or Drinking Water Supplemented with Fructose [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions]

Intestinal Barrier Function and the Gut Microbiome Are Differentially Affected in Mice Fed a Western-Style Diet or Drinking Water Supplemented with Fructose [Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions] Background: The consumption of a Western-style diet (WSD) and high fructose intake are risk factors for metabolic diseases. The underlying mechanisms are largely unclear. Objective: To unravel…

Telomere length predicts cancer risk

Telomere length predicts cancer risk The length of the ‘caps’ of DNA that protect the tips of chromosomes may predict cancer risk and be a potential target for future therapeutics. Longer-than-expected telomeres — which are composed of repeated sequences of DNA and are shortened every time a cell divides — are associated with an increased…

Link between common prostate cancer treatment, dementia detailed in new study

Link between common prostate cancer treatment, dementia detailed in new study A new analysis of patients who have undergone treatment for prostate cancer shows a connection between androgen deprivation therapy (ADT) — a testosterone-lowering therapy and a common treatment for the disease — and dementia, according to researchers. Link between common prostate cancer treatment, dementia…