Proton pump inhibitors do not contribute to dementia or Alzheimer's disease

Proton pump inhibitors do not contribute to dementia or Alzheimer’s disease Noting that the prescription of proton pump inhibitors is on the rise among middle-aged and older adults, a team of researchers designed a new study to examine PPIs and the risk of dementia, mild cognitive impairment, and Alzheimer’s disease. They published their study in…

Alzheimer's gene associated with failure to adapt to cognitive challenge in healthy adults

Alzheimer’s gene associated with failure to adapt to cognitive challenge in healthy adults Healthy adults carrying the gene APOE4 — the strongest known genetic risk factor for Alzheimer’s disease (AD) — may struggle to adapt their brain activity to increasing cognitive demands as they get older, according to a study. Alzheimer’s gene associated with failure…

Newly discovered gene variants link innate immunity and Alzheimer's disease

Newly discovered gene variants link innate immunity and Alzheimer’s disease Three new gene variants, found in a genome wide association study of Alzheimer’s disease (AD), point to the brain’s immune cells in the onset of the disorder. These genes encode three proteins that are found in microglia, cells that are part of the brain’s injury…

Replacing a palatable high-fat diet with low fat food causes withdrawal-like symptoms in mice

Replacing a palatable high-fat diet with low fat food causes withdrawal-like symptoms in mice Researchers have found that mice fed a palatable high-fat diet experience stress responses that resemble drug withdrawal when their food is switched to a low-fat diet. A study has identified brain changes in the dopamine neurotransmitter system caused by stress when…